Journal: Respiratory Research

Article Title: Metabolomic fingerprinting and systemic inflammatory profiling of asthma COPD overlap (ACO)

doi: 10.1186/s12931-020-01390-4

Figure Lengend Snippet: Human Metabolome Database identifiers (HMDB ID), multivariate data analysis (variable influence on projection (VIP) scores, false discovery rate (FDR) adjusted p-value), fold changes and pairwise univariate (ANOVA/Kruskal Wallis test) values are provided for the 11 significantly altered metabolites common to ACO vs. asthma and ACO vs. COPD. Pearson’s correlation coefficient (r) and their significance values ( p value) depicts the association between these altered metabolites and lung function parameters, FEV1, FEV1/FVC of ACO subjects

Article Snippet: The relationship between significantly altered metabolites (common to ACO vs. asthma and ACO vs. COPD) and lung function parameters of ACO subjects was explored using Pearson’s correlation analysis (GraphPad Prism version 7.00 for Windows, GraphPad Software, San Diego, CA, USA).

Techniques:

Journal: Respiratory Research

Article Title: Metabolomic fingerprinting and systemic inflammatory profiling of asthma COPD overlap (ACO)

doi: 10.1186/s12931-020-01390-4

Figure Lengend Snippet: Pearson’s correlation value (r) and significance values (p) depicting the extent to which the 13 dysregulated immunological mediators (significantly altered in ACO vs. asthma, ACO vs. COPD and ACO vs controls) are linearly related to FEV1 and FEV1/FVC of ACO subjects

Article Snippet: The relationship between significantly altered metabolites (common to ACO vs. asthma and ACO vs. COPD) and lung function parameters of ACO subjects was explored using Pearson’s correlation analysis (GraphPad Prism version 7.00 for Windows, GraphPad Software, San Diego, CA, USA).

Techniques: